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Dysgonic fermenter 3-associated gastrointestinal disease in a patient with common variable hypogammaglobulinemia.

Wagner DK, Wright JJ, Ansher AF, Gill VJ.

Metabolism Branch, National Institutes of Health, Bethesda, Maryland.

A gram-negative bacteria designated DF-3 was cultured on multiple occasions from stool samples of a patient with common variable hypogammaglobulinemia and chronic diarrhea. Antibiotic therapy resulted in elimination of the organism and resolution of the patient's symptoms. DF-3 has not been linked previously to human disease; because of its fastidious growth characteristics and unique isolation requirements, it may be a rarely identified cause of diarrhea and other gastrointestinal symptoms in immunocompromised patients.

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PMID: 3407657 [PubMed - indexed for MEDLINE]