Anaphylactic reaction associated with Ranitidine in a patient with acute pancreatitis: a case report.
Rethnam U, Yesupalan RS.
Department of Orthopaedics, Glan Clwyd Hospital, Rhyl, UK. ulfinr@yahoo.com.
ABSTRACT: : Ranitidine is a widely used drug and is known to be well tolerated. This case report illustrates a severe anaphylactic reaction after a single intravenous dose of 50 mgs of ranitidine and highlights this unusual but life threatening adverse reaction. THE PATIENT: A 56 year old female with acute pancreatitis and a known allergy to metronidazole and buscopan developed an anaphylaxis few minutes following the injection of ranitidine for epigastric discomfort. She went on to develop anaphylactic shock and a cardiorespiratory arrest. MANAGEMENT: She was managed with adrenaline, hydrocortisone and ventilatory support following which she had a full recovery. CONCLUSION: Awareness of this rare but life threatening adverse reaction to a commonly used drug can avoid being caught unaware.
PMID: 17764559 [PubMed - in process]PMCID: PMC2018711