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Open Access Case report

Non small-cell lung cancer with metastasis to thigh muscle and mandible: two case reports

Francesca Maria Giugliano1*, Domingo Alberti1, Giovanna Guida1, Giampaolo De Palma1, Luciano Iadanza4, Maria Mormile4, Fabrizio Cammarota1, Agnese Montanino2, Franco Fulciniti3, Vincenzo Ravo1 and Paolo Muto1

Author Affiliations

1 Radiation Therapy Department, National Cancer Institute, Pascale Foundation, Naples, Italy

2 Medical Oncology Unit, Thoraco-Pulmonary Department, National Cancer Institute, Pascale Foundation, Naples, Italy

3 Pathology Unit, National Cancer Institute, Pascale Foundation, Naples, Italy

4 Medical Physics Department, National Cancer Institute, Pascale Foundation, Naples, Italy

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Journal of Medical Case Reports 2013, 7:98  doi:10.1186/1752-1947-7-98

Published: 8 April 2013

Abstract

Introduction

Lung cancer is the leading cause of cancer-related death in Europe and the US. Isolated metastases to skeletal muscle and the mandible are very uncommon.

Case presentation

This report presents two cases. Case 1 concerns a 45-year-old Caucasian woman affected by muscle metastasis of the right thigh from non-small-cell lung cancer. Case 2 concerns a 61-year-old Caucasian man affected by mandible metastasis from non-small-cell lung cancer. Both metastases were detected by diagnostic imaging studies. Both patients were treated with radiation therapy with palliative and antalgic intent.

Conclusion

Radiation therapy was effective and well tolerated in both cases. Both our patients are alive, with follow-up of 18 months and five months, respectively.

Keywords:
Non-small-cell lung cancer; Muscle metastasis; Bone mandible metastasis; Radiation therapy