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Reverse takotsubo cardiomyopathy: two case reports and review of the literature

Gautam R Patankar1, James W Choi24 and Jeffrey M Schussler34*

Author Affiliations

1 Department of Internal Medicine Suite H-102, c/o Suzanne Watts - Program Coordinator, Baylor University Medical Center, 3500 Gaston Avenue, Dallas, TX 75246, USA

2 Baylor University Medical Center, 621 Hall Street #400, Dallas, TX 75226, USA

3 Baylor University Medical Center, 621 North Hall Street Suite 500, Dallas, Texas 75226, USA

4 Texas A&M Health Science Center, College of Medicine, Dallas, Texas, USA

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Journal of Medical Case Reports 2013, 7:84  doi:10.1186/1752-1947-7-84

Published: 19 March 2013



Reverse takotsubo cardiomyopathy is a rare variant of classic takotsubo cardiomyopathy that presents within a different patient profile and with its own hemodynamic considerations. Its recognition is important for prognostic, evaluation and treatment considerations.

Case presentation

Case 1: A 69-year-old Caucasian woman presented with substernal chest pain following a motor vehicle accident. During her evaluation, she was found to have positive results for cardiac enzymes and underwent left heart cardiac catheterization. The results of the catheterization demonstrated no significant coronary stenosis. However, her ventriculogram showed basal and anterior akinesis.

Case 2: A 62-year-old Caucasian woman began having substernal chest pain that radiated to her shoulder blades. She was taken to a local area hospital where she was found to have elevated troponins. A left heart catheterization showed an ejection fraction of 35% with hypokinesis of the anterior and posterobasal walls of her heart, with 30% stenosis of her left anterior descending artery but no other significant coronary artery stenosis.


The cases in this report illustrate a lesser-known variant of takotsubo cardiomyopathy.