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Leiomyosarcoma of the base of the tongue and free edge of the epiglottis: a case report

Adelchi Croce*, Antonio Moretti, Melissa Laus and Domenico Crescenzi*

Author Affiliations

ENT Department, University ‘G. D’Annunzio’ of Chieti-Pescara, Hospital ‘SS. Annunziata’, Via dei Vestini, Chieti, 66100, Italy

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Journal of Medical Case Reports 2012, 6:400  doi:10.1186/1752-1947-6-400

Published: 23 November 2012



We present the case of a man with a leiomyosarcoma of the base of the tongue. We feel this case is important as this kind of pathology, though rare, can occur at a site where carcinomas are more frequent.

Case presentation

A 77-year-old Caucasian man had been reporting difficulty in swallowing and hoarseness for a month before admission to our department. After several preliminary tests, including a biopsy which was positive for a malignant epithelial neoplasm which required further immunohistochemical study, we decided to operate, removing the base of our patient’s tongue and performing a total laryngectomy. Histological examination of the specimen revealed a high-grade leiomyosarcoma of the base of the tongue and of the free edge of the epiglottis.


We wish to stress the rarity of this clinical case, related to the site of implantation of the tumor, as confirmed by the difficulties in finding reference to this topic in the international literature. In fact, several cases of leiomyosarcoma have been described, but in different locations from that seen in our patient’s case.

Base of the tongue; Free edge of the epiglottis; Leiomyosarcoma; Surgery