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Open Access Case report

Sequentially appearing erythema nodosum, erythema multiforme and Henoch-Schönlein purpura in a patient with Mycoplasma pneumoniae infection: a case report

Masaki Shimizu1*, Yasuhito Hamaguchi2, Takashi Matsushita2, Yasuhisa Sakakibara1 and Akihiro Yachie1

Author Affiliations

1 Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa, 920-8641, Japan

2 Department of Dermatology, School of Medicine, Institute of Medical, Pharmaceutical, and Health Sciences, Kanazawa University, 13-1 Takaramachi, Kanazawa, 920-8641, Japan

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Journal of Medical Case Reports 2012, 6:398  doi:10.1186/1752-1947-6-398

Published: 23 November 2012

Abstract

Introduction

A wide variety of skin manifestations are associated with Mycoplasma pneumoniae infection. However, the precise mechanisms by which M. pneumoniae infection is able to produce a variety of cutaneous manifestations are poorly understood.

Case presentation

An 8-year-old Japanese girl presented with sequential skin manifestations, including erythema nodosum, erythema multiforme and Henoch-Schönlein purpura. Although a chest radiograph showed no significant lung abnormalities, serological examinations revealed that these skin manifestations were associated with M. pneumoniae infection.

Conclusion

It has been reported that the variations in cutaneous manifestations of M. pneumoniae infection can be attributed to the immaturity of the adaptive immunity of a host. However, the case presented herein indicates that skin manifestations might not be specific for each individual. An awareness of the varied patterns of cutaneous disease is essential for the early diagnosis and treatment of patients with manifestations of M. pneumoniae infection.

Keywords:
Mycoplasma pneumonia; Erythema nodosum; Erythema multiforme; Henoch-Schönlein purpura