Email updates

Keep up to date with the latest news and content from Journal of Medical Case Reports and BioMed Central.

Open Access Highly Accessed Case report

Intra-medullary tuberculoma of the spinal cord presenting with typhoid and paraplegia: a case report

Sanaullah Bashir1, Akhtar Amin Memon1*, Maryam Sanaullah1 and Yasmeen Hasan2

Author Affiliations

1 Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

2 Department of Neurology, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, Pakistan

For all author emails, please log on.

Journal of Medical Case Reports 2012, 6:388  doi:10.1186/1752-1947-6-388

Published: 13 November 2012

Abstract

Introduction

Intra-medullary spinal tuberculoma is a rare form of tuberculosis, with an incidence of only two in 100,000 patients with tuberculosis. We present a case of intra-medullary tuberculoma from Pakistan, which was diagnosed by radiological findings and analysis of cerebrospinal fluid using polymerase chain reaction testing.

Case presentation

We present the case of a 28-year-old Sindhi male with intra-medullary tuberculoma of the spinal cord at the C3 level. Our patient was treated solely with anti-tubercular drug therapy with no surgical intervention.

Conclusions

We discuss the possible clinical management of such rare cases, considering both chemotherapeutic and surgical options. Additionally, diagnostic procedures and findings are discussed; we suggest cerebrospinal fluid analysis via polymerase chain reaction and gadolinium-diethylenetriamine pentaacetic acid magnetic resonance imaging as important chemical and radiological tests to be performed in such cases.

Keywords:
Intra-medullary tuberculoma; Spinal tuberculoma; Muscle weakness