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Intra-medullary tuberculoma of the spinal cord presenting with typhoid and paraplegia: a case report

Sanaullah Bashir1, Akhtar Amin Memon1*, Maryam Sanaullah1 and Yasmeen Hasan2

Author Affiliations

1 Dow Medical College, Dow University of Health Sciences, Karachi, Pakistan

2 Department of Neurology, Civil Hospital Karachi, Dow University of Health Sciences, Karachi, Pakistan

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Journal of Medical Case Reports 2012, 6:388  doi:10.1186/1752-1947-6-388

Published: 13 November 2012



Intra-medullary spinal tuberculoma is a rare form of tuberculosis, with an incidence of only two in 100,000 patients with tuberculosis. We present a case of intra-medullary tuberculoma from Pakistan, which was diagnosed by radiological findings and analysis of cerebrospinal fluid using polymerase chain reaction testing.

Case presentation

We present the case of a 28-year-old Sindhi male with intra-medullary tuberculoma of the spinal cord at the C3 level. Our patient was treated solely with anti-tubercular drug therapy with no surgical intervention.


We discuss the possible clinical management of such rare cases, considering both chemotherapeutic and surgical options. Additionally, diagnostic procedures and findings are discussed; we suggest cerebrospinal fluid analysis via polymerase chain reaction and gadolinium-diethylenetriamine pentaacetic acid magnetic resonance imaging as important chemical and radiological tests to be performed in such cases.

Intra-medullary tuberculoma; Spinal tuberculoma; Muscle weakness