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Open Access Highly Accessed Case report

Systemic lupus erythematosus associated with sickle-cell disease: a case report and literature review

Mouna Maamar*, Zoubida Tazi-Mezalek, Hicham Harmouche, Wafaa Mounfaloti, Mohammed Adnaoui and Mohammed Aouni

Author Affiliations

Department of Internal Medicine, Ibn Sina Hospital, Rabat, Morocco

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Journal of Medical Case Reports 2012, 6:366  doi:10.1186/1752-1947-6-366

Published: 26 October 2012

Abstract

Introduction

The occurrence of systemic lupus erythematosus has been only rarely reported in patients with sickle-cell disease.

Case presentation

We describe the case of a 23-year-old North-African woman with sickle-cell disease and systemic lupus erythematosus, and discuss the pointers to the diagnosis of this combination of conditions and also present a review of literature. The diagnosis of systemic lupus erythematosus was delayed because our patient’s symptoms were initially attributed to sickle-cell disease.

Conclusions

Physicians should be alerted to the possible association of sickle-cell disease and systemic lupus erythematosus so as not to delay correct diagnosis and initiation of appropriate treatment.

Keywords:
Sickle-cell disease; systemic lupus erythematosus