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Open Access Case report

Gracilis muscle interposition with primary rectal without urethral repair for moderate sized rectourethral fistula caused by brachytherapy for prostate cancer: a case report

Narimantas Evaldas Samalavicius1*, Raimundas Lunevicius2, Rakesh Kumar Gupta3, Tomas Poskus4 and Albertas Ulys1

Author Affiliations

1 Faculty of Medicine, Vilnius University, Oncology Institute, 1 Santariskiu Street, Vilnius, LT 08406, Lithuania

2 King's College Hospital NHS Foundation Trust, King's Health Partners Academic Health Sciences Centre, Denmark Hill, London, SE5 9RS, UK

3 Department of Surgery, B.P. Koirala Institute of Health Sciences, Dharan, Nepal

4 Vilnius University Hospital Santariskiu Klinikos Center Branch, 3 Zygimantu Street, Vilnius, LT 01128, Lithuania

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Journal of Medical Case Reports 2012, 6:323  doi:10.1186/1752-1947-6-323

Published: 25 September 2012

Abstract

Introduction

There is a 0.16% chance of a rectourethral fistula after prostate brachytherapy monotherapy using Palladium-103 or Iodine-125 implants. We present an unusual case report of a rectourethral fistula following brachyradiotherapy monotherapy for prostate adenocarcinoma. It was also associated with unusual management of the fistula.

Case presentation

A 58-year-old Caucasian man underwent brachyradiotherapy monotherapy as definitive treatment for verified intracapsular prostate adenocarcinoma receiving 56 Iodine-125 implants using a transrectal ultrasound-guided technique. The patient started to complain of severe perineal pain and mild rectal bleeding 15Â months after brachyradiotherapy. A biopsy of mucosa of his anterior rectal wall was performed. A moderate sized rectourethral fistula was confirmed 23Â months after implantation of Iodine-125 seeds. Laparoscopic sigmoidostomy and suprapubic cystostomy were then performed. Long-term cortisone applications in combination with 30 sessions of hyperbaric oxygen therapy, and antibacterial therapies were initiated due to necrotic infection. A gracilis muscle interposition to create a partition between the patient's rectum and urethra in conjunction with primary rectal repair but without urethral repair were performed 6 months later. The 3cm rectal defect was repaired via a 3cm-long horizontal perineal incision. The 1.5cm urethral defect just below the prostate was not repaired. The patient underwent an optic internal urethrotomy 3Â months later for a 1.5cm-long urethral stricture. Several planned preventive urethral buginages were performed to avoid urethral stricture recurrence. At 12Â months postoperatively, there were no signs of a fistula and cancer recurrence. He now has a normal voiding and anal continence.

Conclusion

Severe rectal pain, bleeding, and local anterior necrotic proctitis are predictors of a rectourethral fistula. Urinary and fecal diversion is the first-step operation. Gracilis muscle interposition in conjunction with primary rectal repair but without urethral reconstruction is one of the reconstructive surgery options for moderate 2cm to 3cm rectourethral fistulas. Internal urethrotomy is a procedure for postoperative urethral strictures of 1.5cm in length.

Keywords:
Brachytherapy; Gracilis interposition; Prostate cancer; Radiotherapy; Rectal repair; Rectourethral fistula