Open Access Highly Accessed Case report

Mantle cell lymphoma of the larynx: Primary case report

Sarah Naciri1*, Anass A Bennani-Baiti2*, Meriem Glaoui1, Houda Mouzount1, Samia Ghanem1, Leila Essakali2, Mohamed Kzadri2 and Hassan Errihani1

Author Affiliations

1 Medical Oncology Department, National Institute of Oncology, University Mohamed V, University Hospital, Rabat, Morocco

2 Oto-Rhino-Laryngology, Head and Neck Surgery Department, Hopital des Spécialités, University Mohamed V, University Hospital, Rabat, Morocco

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Journal of Medical Case Reports 2012, 6:201 doi:10.1186/1752-1947-6-201

Published: 16 July 2012

Abstract

Introduction

Primary laryngeal lymphomas are exceedingly rare. Only about a hundred cases have been reported. They consist mainly of non-Hodgkin lymphoma, especially of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue. We report the first case of a primary laryngeal mantle cell lymphoma.

Case presentation

We report a case of a primary mantle cell lymphoma of the larynx in a 70-year-old North African non-smoker male. We present a detailed report of his clinical and paraclinical data as well as treatment options.

Conclusions

Mantle cell lymphoma is a very aggressive lymphoma subset associated with poor prognosis. Laryngeal mantle cell lymphoma is exceedingly rare. To the best of our knowledge, this is the first case to ever be reported.