Unusual computed tomography findings of radionecrosis after chemoradiation of stage IV hypopharyngeal cancer: a case report
1 Department of Otorhinolaryngology, Ohtawara Red Cross Hospital, 2-7-3 Sumiyoshi-cho, Ohtawara City, Tochigi 324-8686, Japan
2 Department of Otorhinolaryngology, Head and Neck Surgery, Keio University, 35 Shinanomachi Shinjuku, Tokyo 160-0082, Japan
3 Department of Biochemistry & Molecular Biology, Kanagawa Dental College, Yokosuka 238-8580, Japan
Journal of Medical Case Reports 2011, 5:25 doi:10.1186/1752-1947-5-25Published: 20 January 2011
Radionecrosis (post-radiotherapy laryngeal submucosal inflammation and necrosis) is a complication of (chemo) radiotherapy for hypopharyngeal cancer that is difficult to differentiate from tumor recurrence.
A 67-year-old Japanese man presented with a condition extremely difficult to diagnose differentially as radionecrosis or tumor recurrence after radiotherapy for hypopharyngeal cancer. Although tumor recurrence was suspected from clinical conditions and computed tomography findings, pathologic analysis revealed no evidence of tumor recurrence, and successful therapy with steroids and antibiotics reduced the mucosal edema.
Our findings emphasize the wide spectrum of radiographic presentation of radionecrosis after chemoradiation of stage IV hypopharyngeal cancer.