Email updates

Keep up to date with the latest news and content from Journal of Medical Case Reports and BioMed Central.

Open Access Open Badges Case report

Unusual computed tomography findings of radionecrosis after chemoradiation of stage IV hypopharyngeal cancer: a case report

Yuh Baba123*, Yasumasa Kato3 and Kaoru Ogawa2

Author Affiliations

1 Department of Otorhinolaryngology, Ohtawara Red Cross Hospital, 2-7-3 Sumiyoshi-cho, Ohtawara City, Tochigi 324-8686, Japan

2 Department of Otorhinolaryngology, Head and Neck Surgery, Keio University, 35 Shinanomachi Shinjuku, Tokyo 160-0082, Japan

3 Department of Biochemistry & Molecular Biology, Kanagawa Dental College, Yokosuka 238-8580, Japan

For all author emails, please log on.

Journal of Medical Case Reports 2011, 5:25  doi:10.1186/1752-1947-5-25

Published: 20 January 2011



Radionecrosis (post-radiotherapy laryngeal submucosal inflammation and necrosis) is a complication of (chemo) radiotherapy for hypopharyngeal cancer that is difficult to differentiate from tumor recurrence.

Case presentation

A 67-year-old Japanese man presented with a condition extremely difficult to diagnose differentially as radionecrosis or tumor recurrence after radiotherapy for hypopharyngeal cancer. Although tumor recurrence was suspected from clinical conditions and computed tomography findings, pathologic analysis revealed no evidence of tumor recurrence, and successful therapy with steroids and antibiotics reduced the mucosal edema.


Our findings emphasize the wide spectrum of radiographic presentation of radionecrosis after chemoradiation of stage IV hypopharyngeal cancer.