Open Access Highly Accessed Case report

Extragonadal germ cell tumor presenting in a woman with systemic lupus erythematosus: a case report

Mohd Shahrir*, Abdul Halim, Soehardy Zainudin, Rozita Mohamad, Loo C Yuen, Rashidi Saidin and Norella Kong

Author Affiliations

Department of Medicine, Faculty of Medicine, Universiti Kebangsaan, Malaysia

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Journal of Medical Case Reports 2010, 4:97 doi:10.1186/1752-1947-4-97

Published: 25 March 2010

Abstract

Introduction

Germ cell tumor of the pituitary gland is a very rare occurrence.

Case presentation

We describe the case of a 28-year-old Malaysian Malay woman with lupus nephritis who complained of a three month headache and blurring of vision. She was found to have a pituitary mass, which was later proven to be a germ cell tumor. As of writing this case report, her disease is in remission.

Conclusion

The disruption of the pituitary gonad axis could affect the disease activity by reducing immunoregulatory control.