|
Endocrine evaluation of the patient at 14 and 20 years of age |
||
| Age (years) |
14 |
20 |
| Skeletal age (years) |
10 |
Closed epiphysis |
| Weight (kg) |
25.7 |
39.8 |
| Height (m) |
1.19 |
1.41 |
| FSH levels (mIU/ml), (Basal/peak response to LHRH stimulation) |
0.90/4.90 |
9.27/11.6 |
| LH levels (mIU/ml), (Basal/peak response to LHRH stimulation) |
0.70/9.70 |
9.57/50.9 |
| Estradiol levels (pg/ml), (Basal/to LHRH stimulated response) |
5/20 |
31.1/315.0 |
| GH levels (ng/ml), (Basal/peak response to L-Dopa stimulation, following estradiol priming) |
0.93/6.10 |
- |
| GH levels (ng/ml), (Basal/peak response to insulin-induced hypoglycemia when the lowest glucose was 26 mg/dl)) |
- |
0.37/5.18 |
| Overnight GH profile (ng/ml), (Frequent sampling from 10 00 pm to 10 00 am) |
- |
0.07/0.12/0.37/0.11/0.05/0.24 |
| IGFBP3(ng/ml) |
2941 |
- |
| Basal IGF1 (ng/ml) |
17.5 |
50.8 |
| TSH levels (mU/ml), (Basal/peak response to TRH stimulation) |
4.6/14.5 |
4.57/21.97 |
| Basal FT4 (pmol/l) |
16.7 |
12.71 |
| Cortisol levels (μg/dl) (Basal/peak response to insulin-induced hypoglycemia) |
- |
9.9/20.2 |
|
Normal values for basal growth hormone (GH): 0 to 7 ng/ml; insulin-like growth factor1 (IGF1), for 12- to 15-year-old girls: 261 to 1096 ng/ml, for 16- to 24-year-old women: 182 to 780 ng/ml; insulin-like growth factor binding protein 3 (IGFBP3), for 7 to 39 year olds: 1250 to 7330 ng/ml; normal GH response to insulin-induced hypoglycemia >5.0 ng/ml; severe GH deficiency in insulin-induced hypoglycemia <3.0 ng/ml; normal GH response to L-Dopa >10 ng/ml. | ||
Dagdelen et al. Journal of Medical Case Reports 2008 2:210 doi:10.1186/1752-1947-2-210 |
||