Journal of Medical Case Reports
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Case reportOsseous metaplasia in an ulcerating tubular adenoma of the colon: a case reportVictoria White1 , Aidan G Shaw2 , Gillian M Tierney1 , Jonathan N Lund2 and David Semeraro3  1
Department of Colorectal Surgery, Derby City General Hospital, Derby, UK 2
School of Graduate Medicine and Health, University of Nottingham United Kingdom, Derby, DE22 3DT, UK 3
Department of Histopathology, Derby City General Hospital, Derby, UK author email corresponding author email
Journal of Medical Case Reports 2008,
2:130doi:10.1186/1752-1947-2-130 Abstract
Introduction
Heterotopic bone is rarely found in the gastrointestinal tract. Here we report a rare case of metaplastic ossification within a benign ulcerating adenoma and review the literature concerning the aetiology.
Case presentation
A 63-year-old woman, who presented with a history of melaena, was found at colonoscopy to have a pedunculated ulcerating polyp. Histological examination demonstrated multiple areas of osseous metaplasia within the polyp stroma.
Conclusion
Heterotopic ossification in colonic adenomas is a particularly rare phenomenon, with the majority of cases occurring within malignant lesions. The suggested mechanisms for its aetiology still remain unclear. |