Table 1

Summary of patient's clinical findings relative to acromegaly and the three hereditary cancer susceptibility syndromes considered

Patient's Findings
Acromegaly
Hereditary Syndrome





Cowden syndrome
Carney complex
MEN1

Seminoma
X

XX*

Pituitary adenoma (GH-producing)
XX

XX
XX
Colon adenomatous polyps
XX



Colon harmatomatous polyps

XX


Colon hyperplastic polyps




Renal cell carcinoma
X
X


Lipomas

XX

XX
Lentigines


XX


XX: Classical syndrome-related findings

X: Findings are less clearly established as part of the syndrome

* Testicular cancers associated with Carney complex are typically large-cell calcifying Sertoli cell tumors or Leydig cells tumors of the testis

Mai et al. Journal of Medical Case Reports 2007 1:9   doi:10.1186/1752-1947-1-9