|
Published reports of bupropion hepatotoxicity |
|||||
| Author (yr) |
Dose |
Duration of use (Days) |
Peak ALT (IU/L) |
Peak bilirubin (mg/dl) |
Outcome |
|
|
|||||
| Oslin ('93) |
300 mg QD × 21 days, then 400 mg QD |
54 |
5.4 × ULN |
Not reported |
Resolution |
| Hu ('00) |
200 mg QD |
42 |
6660 |
3.8 |
Resolution |
| D. Alvaro ('01) |
150 mg BID |
20 |
49 × ULN |
38 |
Resolution |
| Humayun ('07) |
150 mg BID |
180 |
20 × ULN |
37 |
Death |
|
ULN = Upper limit of normal | |||||
Humayun et al. Journal of Medical Case Reports 2007 1:88 doi:10.1186/1752-1947-1-88 |
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