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Open Access Case report

Severe hypercalcaemia and lymphoma in an HTLV-1 positive Jamaican woman: a case report

Veronica Lyell*, Elham Khatamzas and Theresa Allain

Author Affiliations

Department of Care of the Elderly, Southmead Hospital, Bristol, UK

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Journal of Medical Case Reports 2007, 1:56  doi:10.1186/1752-1947-1-56

Published: 25 July 2007

Abstract

Human T cell lymphotrophic virus type-1 infection is endemic in the Afro-Caribbean community in Britain, with carriage rates of about 3%. Although there is a long latency, carriers have a 1–5% chance of developing adult T cell leukaemia/lymphoma, a condition frequently complicated by marked and refractory hypercalcaemia, and with a poor prognosis. We present the case of an elderly Jamaican woman with severe hypercalcaemia and a raised PTHrP who was found to have lymphoma and was positive for HTLV-1.