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Atrial and placental melanoma metastasis: a case report and literature review

Pradeep Lakshminarayana1 email, Sarah Danson1 email, Kim Suvarna2 email and Barry Hancock1 email

Department of Clinical Oncology, Weston Park Hospital, Whitham Road, Sheffield, S10 2SJ, UK

Department of Histopathology, Northern General Hospital, Herries Road, Sheffield, S5 7AU, UK

author email corresponding author email

Journal of Medical Case Reports 2007, 1:21doi:10.1186/1752-1947-1-21

Published: 14 May 2007

Abstract

Malignant melanoma can metastasize to virtually any organ of the body. The aggressiveness is determined by the primary site, depth of dermal invasion, presence or absence of ulceration, lymphovascular infiltration and regional lymph node involvement. We report a case of a pregnant woman with a previous history of stage 3 melanoma who presented with cardiac metastasis and placental melanoma infiltration. A review of literature on cardiac and placental involvement of melanoma is also provided.


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