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Open Access Case report

Multiple metachronous malignancies, one patient with three primary malignancies: a case report

Horace Fletcher1*, Gilian Wharfe2, Elaine Williams2, Barrie Hanchard2 and Derek Mitchell3

Author Affiliations

1 Department of Obstetrics and Gynaecology, University of the West Indies, Mona, Kingston, Jamaica

2 Department of Pathology, University of the West Indies, Mona, Kingston, Jamaica

3 Department of Surgery, University of the West Indies, Mona, Kingston, Jamaica

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Journal of Medical Case Reports 2007, 1:15  doi:10.1186/1752-1947-1-15

Published: 2 May 2007

Abstract

We present a 61 year old Para 4 woman who presented with stage II Infiltrating lobular carcinoma of the breast after modified radical mastectomy. She was treated with Tamoxifen for seven years. She was diagnosed with multiple myeloma during year seven post mastectomy because of wrist pain. She was treated with melphalan, prednisone and allopurinol which she tolerated well and the pain in the wrist improved. Tamoxifen was also stopped. Ten months later she presented with vaginal bleeding and was diagnosed with a poorly differentiated endometrial adenocarcinoma at hysteroscopic suction curettage and had an abdominal hysterectomy. Two years later the patient succumbed to metastatic endometrial cancer.