Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report

doi:10.1186/1752-1947-1-10

Journal of Medical Case Reports

Volume 1

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Kawashima M
Mochizuki H
Kawakita T
Hatoh S
Shimazaki J
Yamada M

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Mochizuki H
Kawakita T
Hatoh S
Shimazaki J
Yamada M
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Case report

Presumed stromal graft rejection after automated lamellar therapeutic keratoplasty: case report

Motoko Kawashima¹^,2 , Hiroshi Mochizuki² , Tetsuya Kawakita¹ , Shin Hatoh² , Jun Shimazaki¹ and Masakazu Yamada²

¹Department of Ophthalmology, Tokyo Dental College, Chiba, Japan

²Division for Vision Research, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, Japan

author email corresponding author email

Journal of Medical Case Reports 2007, 1:10doi:10.1186/1752-1947-1-10


Published:	1 April 2007

Abstract

Purpose

To describe the development of presumed immune-mediated stromal rejection after automated lamellar therapeutic keratoplasty (ALTK) and its reversal after initiation of intensive topical corticosteroid therapy.

Methods

Observational case report.

Results

Stromal edema localized in the graft developed 42 days after ALTK for Avellino corneal dystrophy in a 65-year-old man. After one week of intensive topical corticosteroids, complete reversal of graft edema occurred, with full recovery of visual function.

Conclusion

The clinical appearance and response to therapy in this case supported the diagnosis of immune-mediated stromal rejection. Ophthalmologists should be aware that stromal rejection may occur in lamellar corneal grafts.